Dr. Tim O’Connor, MD
Psychiatrist
FDA-Approved Treatment for Severe Depression
In-Network with Insurance
No Waitlist
In addition to offering Transcranial Magnetical Stimulation (TMS) for treatment-resistant depression at our Raleigh location, we also offer psychiatry and therapy across all of our locations in Raleigh, Chapel Hill, Cary, and Telehealth across North Carolina.
TMS often works best when combined with therapy and psychiatric care. As an integrated practice, we can coordinate these services together to give you more complete and connected support.
Transcranial magnetic stimulation (TMS) is a therapy that uses magnetic fields to activate nerve cells in the brain. We primarily use it to treat treatment-resistant depression, meaning depression that hasn’t improved with medication or other treatments.
However, TMS can also help with other conditions, including obsessive-compulsive disorder (OCD), anxiety, PTSD, Parkinson’s disease, and smoking cessation.
TMS did not happen overnight. It began in 1985 when a team of researchers in England made a breakthrough: they discovered that magnetic pulses delivered outside the skull could activate nerve cells inside the brain — precisely enough to cause a volunteer’s hand to move on command. It was a moment that laid the foundation for TMS.
What followed was decades of clinical research to understand what else this technology could do. Over time, that work earned formal recognition from the FDA — approving TMS for treatment-resistant depression in 2008, OCD in 2018, and smoking cessation in 2020.
FDA Approval Timeline:
To understand TMS, it helps to understand what’s happening in the brain when someone has depression.
In people with treatment-resistant depression, certain areas of the brain — particularly the prefrontal cortex, which regulates mood — show reduced activity. The nerve cells in these regions are not communicating the way they should, and antidepressants alone are not enough to fix that for everyone.
TMS targets this directly. The device delivers focused magnetic pulses to the underactive areas of the brain. Those pulses create small electrical currents that stimulate the nerve cells, encouraging them to fire and communicate more effectively. Over the course of a full treatment cycle, this repeated stimulation essentially helps rewire those neural pathways — restoring activity in regions that depression has quieted.
Think of TMS like physical therapy for the brain. Just as repeated exercises rebuild strength in an injured muscle, repeated TMS sessions rebuild healthy activity patterns in areas of the brain affected by depression. The effects are not immediate, which is why a full course of TMS treatment spanning several weeks is necessary to see lasting results.
Unlike medication, TMS does not introduce any chemical into your body. It works entirely through targeted magnetic stimulation, which is why it does not carry the same side effects that many antidepressants do.
If you are considering TMS, there is a good chance you have already tried antidepressants.
Here is how the two approaches compare:
Antidepressants work by adjusting the levels of neurotransmitters like serotonin and dopamine throughout your entire body. TMS works differently — it targets specific regions of the brain directly with magnetic pulses, without introducing any substance into your system.
Antidepressants are typically the first line of treatment for depression and work well for many people. TMS is specifically designed for patients who have tried antidepressants and not found adequate relief — what clinicians call treatment-resistant depression.
Antidepressants can cause a wide range of systemic side effects including weight changes, sexual dysfunction, sleep disruption, and emotional blunting.
TMS side effects are localized and mild — most commonly a slight headache or scalp discomfort during the first few sessions that fades over time.
Both antidepressants and TMS take time to work. Antidepressants typically require four to six weeks before a meaningful change in mood is felt. With TMS, most patients begin noticing improvement within the first one to two weeks of treatment, though the full benefit is usually felt after completing the entire course.
Yes. TMS and antidepressants are able to be combined. Many patients continue their medication while undergoing TMS, and research suggests the combination can improve outcomes for both treatments.
TMS was initially used for treatment-resistant depression and has stood the test of time as an effective treatment for depression.
Over the years, TMS has shown promise for other conditions. While we only use TMS for depression, it can be useful to understand other conditions it treats.
Up to 30% of people with depression do not respond to antidepressant medication. TMS was designed with these patients in mind.
Studies show that TMS not only reduces depression symptoms but helps more than one-third of patients reach full remission.
A large overview of 81 studies with over 4,000 patients confirmed that TMS significantly outperformed placebo treatment.
TMS has shown strong results for OCD. In clinical research, 38% of patients who received TMS reported meaningful symptom improvement, compared to just 11% in the placebo group.
In a pilot study, 90% of patients who received TMS for smoking reported staying smoke-free and having fewer cravings at a 25-day follow-up. These results have been supported by other similar studies.
While research is still growing, TMS shows early promise for both anxiety disorders and PTSD, particularly for patients who have not found relief through medication or therapy alone.
Not all TMS is the same. There are three main types, each designed to deliver magnetic stimulation in a slightly different way — some reach deeper into the brain, while others focus on specific surface-level regions.
Understanding the differences can help you feel more confident going into treatment. Your provider will review your history and recommend the approach that is the best fit for you — there is no one-size-fits-all answer here.
The original form of TMS, used primarily in research settings. Single pulses are delivered to measure brain activity and response.
This is the most common type used in clinical treatment. rTMS delivers magnetic pulses at a set pace to areas of the brain connected to depression. The repeated stimulation helps rewire communication between nerve cells, which can ease depressive symptoms over time.
Deep TMS is the primary type of TMS therapy that we use. Deep TMS uses a different design that reaches further into the brain than standard rTMS. This allows it to stimulate deeper regions that play a role in mood and behavior. Research shows dTMS improved symptoms in over 75% of patients with major depressive disorder, often with fewer side effects.
TMS is done in an outpatient setting. You sit in a reclined chair while one of our team members places a small, lightweight device against your head — similar to a helmet or headset. It rests comfortably near the area of the brain being treated and never breaks the skin or requires any kind of insertion.
Each session typically lasts between 20 and 40 minutes. Most treatment courses run 5 days a week for 4 to 6 weeks. During the session you will hear a clicking sound and feel a gentle tapping sensation on your scalp — most patients adjust to this quickly. You are fully awake the entire time with no sedation needed. When the session ends, you can drive yourself home and return to your normal day right away.
Most people can return to their regular routine immediately after each session. Some patients begin to notice mood improvements after the first one to two weeks, though it can take longer depending on the individual. Results vary based on factors like the severity of your condition, your overall health, and whether you are using other treatments at the same time.
TMS is considered safe and well-tolerated by most patients. The most common side effects are mild and can include:
These side effects typically fade after the first few sessions. If they persist, our care team can work with you to adjust the intensity of the stimulation or recommend over-the-counter pain relief.
Like any other medical treatment, TMS is not right for everyone. Because TMS works by delivering magnetic pulses to the brain, certain medical conditions or implants can make it unsafe or less effective.
That is why a thorough evaluation with your provider is always the first step — not just to confirm you are a good candidate, but to make sure treatment is tailored to your specific situation.
You may not be a candidate for TMS if you have:
This list is not exhaustive. Always share your full medical history with your provider before starting TMS, including any medications you are taking and any past procedures or surgeries. If something disqualifies you from TMS, our care team will work with you to find an alternative path forward — being ineligible for one treatment does not mean you are out of options.
Yes, and it often works better when it is. Many patients receive TMS alongside antidepressant medication, cognitive behavioral therapy (CBT), or other forms of psychotherapy. Combining treatments allows your care team to address depression from multiple angles at once, which can lead to stronger and longer-lasting results.
Insurance coverage for TMS has expanded significantly since its FDA approval. Many major insurance providers cover TMS for treatment-resistant depression, though requirements vary by plan.
Medicare and Medicaid coverage varies and is not always guaranteed. We recommend contacting your insurance provider directly to confirm your benefits before starting treatment.
Keep in mind, our team is always available to help you navigate the insurance process.
This can be a common concern, especially if you’ve tried multiple depression treatments. While TMS is effective for many people, it is not a guaranteed solution for everyone. If you complete a full course of TMS and do not see the improvement you were hoping for, that does not mean you are out of options. Depression and other mental health conditions often require trying more than one approach before finding what works.
Our team will work with you to review your response, adjust the treatment plan if needed, and explore other evidence-based options. You deserve care that fits your needs — and we will keep looking until we find it.
Psychiatrist
Psychiatric Physician Assistant
Psychiatric Physician Assistant
Clinical Therapist
At the core of AIM is our dedicated team, focused on fostering an environment where optimal wellbeing is achievable.
Driven by a vision of accessible, compassionate healthcare, our diverse professionals bring unique expertise and insights to enhance our mission. We believe in the power of connection and collaborative care. From clinical experts to supportive staff, every team member contributes to creating a nurturing environment that promotes growth, healing, and comprehensive wellbeing.
Step 1: Fill out the New Patient Form.
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Step 3: Pick your provider, date, and time
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